How a Diabetes Drug Reverses Alzheimer’s-Related Memory Loss

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Laboratory research in the United Kingdom has recently uncovered that a medication designed to treat diabetes may hold the secret to memory loss reversal in seniors with Alzheimer’s disease. The results have proven successful during animal testing. Clinical trials on people may be the next step. 

Lancaster University Study 

An article published in the journal Brain Research explained that scientists from Lancaster University determined a triple receptor drug holds potential for treating Alzheimer’s disease. The study involved laboratory mice who were bred to have the inherited form of Alzheimer’s. Once the disease process advanced, some of the mice were given the medication. After receiving the drug, all the mice were encouraged to navigate a maze. 

The animals receiving the triple agonist medication demonstrated better learning and memory abilities. Physiological evaluations revealed that the treated mice also had a reduced amount of plaque buildup in their brains. The rodents also exhibited reduced inflammation and neuron loss. The scientists concluded that the treated animals had the benefit of increased neuron protection. The results of the trial indicate that the new medication offers hope for people living with neurodegenerative health conditions such as Alzheimer’s disease. 

As researchers have not developed a promising treatment for Alzheimer’s disease in more than a decade, the latest study thrills scientists. Additionally, as the Alzheimer’s population is estimated to triple in the next three decades, the success of the new medication is of the utmost importance. 

The days, weeks, and months following an Alzheimer’s diagnosis can be challenging for both seniors and their families. However, these challenges can be made less stressful with the help of caregivers trained in professional Alzheimer’s care. Fairfield, Connecticut, Home Care Assistance is here to help your loved one enjoy the golden years while simultaneously managing the symptoms of Alzheimer’s.

Triple Agonists

The medication belongs to a classification of drugs known as triple receptors because the formula contains GLP-1, GIP, and glucagon, which are all growth factors. In the brains of seniors with Alzheimer’s disease, these substances are prevented from being produced or from carrying on their normal function. Without the growth factors, neurons gradually lose their functioning ability, which leads to Alzheimer’s symptoms. So far, in laboratory animals, the new triple agonist medication inhibits the effects of neurodegeneration while encouraging cell growth. 

Older adults with Alzheimer’s disease can also benefit from receiving regular mental stimulation by professionally trained caregivers. Families looking to hire a Fairfield elderly caregiver can reach out to Home Care Assistance. All of our hourly and live-in caregivers receive extensive ongoing training to ensure they provide the high-quality in-home care seniors need and deserve.

The Alzheimer’s Diabetes Connection 

For decades, people believed diabetes occurred due to changes in the liver and the pancreas. However, researchers have now determined the underlying cause of diabetes to be the changes that first take place in the brain. The hormone insulin has natural neural protection properties and certain growth factors.

The new theory influenced scientists to perform research using the diabetes medication known as liraglutide, which contains the glucagon-like peptide-1, also known as GLP-1. The formula acts as a receptor agonist. When administered to laboratory animals, the medication dramatically enhanced the cognitive function of rodents with Alzheimer’s disease. Later testing uncovered similar results in hundreds of human test subjects. As the medication demonstrated effectiveness, the development of a triple-receptor agonist was thought to offer more neural protection and benefits.

Using medications is just one of the many ways older adults can boost their health and wellbeing. Seniors who want to remain healthy as they age can benefit in a variety of ways when they receive professional non-medical home care. Fairfield, CT, Home Care Assistance is here to help your loved one accomplish daily tasks, prevent illness, and focus on living a healthier and more fulfilling life. To create a comprehensive in-home care plan for your aging loved one, call us at 203-955-1915 today.